Type 2 Diabetes Mellitus – Summary of Initial Management and Monitoring
This post is a really brief summary of NICE guidance and QOF - should be useful for AKT and actually managing newly diagnosed diabetic patients or for a refresher on monitoring…
New diabetics need a few referrals, coding and adding to follow up clinics
They need annual BP, BMI, foot check, cardiovascular screen and bloods – HbA1c, LFT, U/E, lipids,
There are 6 oral medications, insulin, statins and antihypertensives
Each medication has different monitoring but if in doubt start with the full list above and then repeat every 3, 6 or 12 months until a stable low HbA1c is achieved.
Relevant Guidelines and Summary Documents
Moran G M, Bakhai C, Song S H, Agwu J C. Type 2 diabetes: summary of updated NICE guidance BMJ 2022; 377 :o775 doi:10.1136/bmj.o775
https://cks.nice.org.uk/topics/diabetes-type-2/
Suspect a diagnosis of type 2 diabetes if there is:
Persistent hyperglycaemia.
Polydipsia, polyuria, weight loss, tiredness; enuresis, behavioural changes,
Impaired growth (in children);
Signs of acanthosis nigricans (suggesting insulin resistance).
Diagnosis = HbA1c >48 mmol/mol [6.5%]
Random plasma glucose >11.1 mmol/l
Fasting plasma glucose >7.0 mmol/L
If symptomatic – a single reading is diagnostic, a repeat is sensible
If asymptomatic, then 2x high readings = diagnostic
Fructosamin = alternative with haemoglobinopathy
Management of a person with type 2 diabetes should include:
(Doctor Responsibilities)
NICE Quality statement 1: Borderline diabetic patients are offered an intensive lifestyle-change programme
Send self-referral letter via Accurx
Quality statement 2: Offer structured education programme at diagnosis
Refer to nurses, task reception
(No 3 seems to be missing on the website)…Quality statement 4: After 6/12 single therapy if HbA1c level > 58 mmol/mol (7.5%)
Offer dual therapy
Quality statement 5: High risk patients are referred to the foot protection service.
Quality statement 6: Adults with a limb-threatening or life-threatening diabetic foot problem are referred immediately for specialist assessment and treatment.
Refer for retinopathy screening
Advising on how to manage intercurrent illness and 'sick-day rules'.
Advising against routine self-monitoring of blood glucose levels.
Assessing for associated psychosocial problems and offering support.
Advising on sexual health, contraception, and pre-pregnancy counselling, if appropriate.
Advising on the importance of regular screening for complications, how to reduce risk, and offering management as appropriate.
For children:
a. Quality statement 1: referred to a multidisciplinary paediatric diabetes team on the same day.
b. Quality statement 2: offer a programme of diabetes education from diagnosis
c. Quality statement 6: offer access to mental health professionals
Advising on the importance of regular HbA1c monitoring, antidiabetic drug treatment (if appropriate), and individualized treatment targets, to reduce the risk of long-term complications.
T2DM Medical Management
Metformin (1) = 1st line
Check U/E and eGFR before starting
Annually eGFR if normal function, otherwise twice yearly
Gradually increase dose
Stop Metformin if eGFR <30 mL/min/1.73 m2 or acutely unwell
Caution – renal impairment, acutely unwell
SGLT-2 inhibitors (4) = 2nd line for most people
Caution – DKA risk, acutely unwell, low carb or keto diet, renal impairment, liver failure, lower leg skin lesions, hypotension, Lithium treatment, thrush and UTI risk,
Must be documented that you warned about fournierres gangrene
Due to the hypotension risk patients should be monitoring their BP at home. Consider reducing antihypertensives when starting.
Gradually increase dose
Check U/E and eGFR and LFT before starting
Annually eGFR if normal function, otherwise twice yearly
Sulfonylureas (5)
Caution – obesity (weight gain) or renal impairment
Patients must be warned about hypoglycaemia and test their BM regularly
DPP-4 inhibitors (5)
Check U/E and eGFR before starting and LFTs
Annually eGFR if normal function, otherwise twice yearly
Vildagliptin: LFT 3/12 for the first year, and periodically thereafter.
Caution – renal impairment, liver failure, heart failure
Pioglitazone (1)
Check LFT before starting
Caution – heart failure, osteoporosis, high risk of bladder cancer, haematuria
Reassess at 3/12 and 6/12
Monitor LFT and signs of heart failure
GLP-1 receptor agonists (5)
Caution – ketoacidosis, pancreatitis, renal impairment, hepatic impairment, GI disease, women of child bearing age, heart failure, thyroid disease, retinopathy
Should only be started by a clinician confident in their use
QOF DM006 – Dx of nephropathy
Proteinuria or micro-albuminuria – ACE-I or ARB
QOF DM022 in last 36 months recorded –
age >40, CVD QRISK2 <10% on a statin
QOF DM023 in last 12 months recorded – History of IHD on a statin
Elevated lifetime risk of cardiovascular disease
Defined as the presence of ≥1 cardiovascular risk factor in someone aged <40 years = hypertension, dyslipidaemia, smoking, obesity, family history (in a first degree relative) of premature cardiovascular disease
Start a statin
If dual therapy doesn’t control blood glucose then consider starting Insulin
Management of a person with type 2 diabetes should include:
(Nurse Responsibilities)
1. Ensuring they have an individualized care plan, taking into account their age, preferences, co-morbidities, and risks and benefits of treatment.
2. Advising on sources of information and support.
3. Advising on always wearing or carrying some form of diabetes identification.
4. Advising on lifestyle measures, such as diet, exercise and physical activity, weight loss, smoking, alcohol, and drug misuse.
5. Ensuring young people are supported in the transition from paediatric to adult services.
6. QOF DM017 – keep a register of all diabetes patients
7. QOF DM002 in last 12 months recorded – BP <150/90
8. QOF DM003 in last 12 months recorded - BP <140/80
9. QOF DM004 in last 12 months recorded – total cholesterol < 5
10. QOF DM005 in last 12 months recorded – ACR recorded
11. QOF DM007 in last 12 months recorded – HbA1c <59
12. QOF DM008 in last 12 months recorded – HbA1c <64
13. QOF DM009 in last 12 months recorded – HbA1c <75
14. QOF DM011 in last 12 months recorded – retinal screening
15. QOF DM012 in last 12 months recorded – foot examination and risk score
16. QOF DM014 in last 9 months recorded – referred to structured education
17. QOF DM018 in last 12 months recorded – influenza and pneumococcal immunisation
18. QOF DM019/20/21 without moderate/severe frailty – BP and HbA1c
19. QOF DM022 in last 36 months recorded – age >40, CVD QRISK2 <10% on a statin
20. SMOK002 in last 12 months recorded – current smokers offered smoking cessation = CHD, PAD, stroke or TIA, hypertension, diabetes, COPD, CKD, asthma, schizophrenia, bipolar affective disorder or other psychoses
Dr David Unwin has done some groundbreaking work with diabetes in his UK practice. He's shaved tens of thousands of pounds off his surgerys budget for medication and managed hundreds of patients safely and successfully through treatment via a dietary approach (obviously with close monitoring and follow up) Most no longer require exogenous insulin. Such an amazing and humble GP who I was honoured to listen to lecture at Sydney University. His work is very promising although I believe he is now retired I hope others carry his ideas forwards.