No 37 - My plan for learning the history of modern medications

Building on from No 36, i’ve been giving this some more thought.

https://medicurious.substack.com/p/no-36-searching-for-the-ideal-history?r=p3tn3&s=w&utm_campaign=post&utm_medium=web&utm_source=direct

My plan for the next few months is to pick common conditions like hypertension and review them in depth.

My plan is to try and summarise the following:

1. When was the condition described and by who?

2. What is the natural course?

3. What are the signs and symptoms?

4. What is the natural mortality and morbidity rate?

5. Are you likely to die from this or something else?

6. What was the first treatment and was it effective?

7. When was the first trial? And by whom?

8. When was the first guidline?

9. What is the current management?

10. What is the risk reduction?

11. What is the NNT for each medication?

12. When was each medication discovered and by whom?

13. What are the major studies in this field?

14. At some point, I will have to learn the side effects and drug interactions.

15. A summary of the evidence of the current management.

Anything else I should include?